Botanical
Ashwagandha
Withania somnifera
Adaptogenic herb used in Ayurvedic medicine. No FDA RDI; declared with † symbol. Standardized extracts typically contain 5% withanolides.
RDI † not establishedVoluntary3 Forms
Used in 1 Template3 FDA Q&A
15 Ingredients · FDA Reference Data
Supplement Ingredients Database
Reference data for high-frequency supplement ingredients — FDA RDI values, mandatory declaration status, common forms, and 21 CFR 101.36 label formatting rules.
RDI from FDA 21 CFR 101.9Cross-checked with NIH ODSLast updated 2026
Most Searched FDA Questions
Quick answers to the most common ingredient label questions — sourced from our database.
Vitamin/ingredients/vitamin-d3
What is the FDA RDI for Vitamin D3 on Supplement Facts labels?
The FDA Reference Daily Intake (RDI) for Vitamin D is 20 mcg (800 IU) per day for adults and children 4 years and older, established under 21 CFR 101.9(c)(8)(iv). This value applies to both D2 and D3 forms. Supplement Facts labels must declare vitamin D in mcg; IU may appear as a secondary declaration in parentheses.
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Mineral/ingredients/calcium
Why is calcium mandatory on Supplement Facts labels?
FDA 21 CFR 101.36(b)(2)(i) designates calcium as one of four mandatory dietary ingredients (with vitamin D, iron, and potassium) due to its public health significance for bone health. If a supplement contains any amount of calcium, it must be declared with amount and %DV. If absent, the label must still show "Calcium 0 mg 0%".
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Mineral/ingredients/magnesium
Do I declare the salt weight or elemental magnesium on my Supplement Facts label?
FDA 21 CFR 101.36(b)(2)(ii) requires declaration of elemental magnesium, not the salt weight. For example, if your formula contains 1000 mg of Magnesium Glycinate (~14.1% elemental Mg), the Supplement Facts panel should declare "Magnesium 141 mg 34%" — not "Magnesium Glycinate 1000 mg". The salt form may appear in the ingredient list separately.
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Mineral/ingredients/iron
Are there special FDA labeling requirements for iron supplements?
Yes. FDA requires warning labels on iron-containing supplements (21 CFR 101.17(e)) regarding accidental overdose in children under 6. Products with 30 mg or more of elemental iron per dosage unit must include specific warning language about keeping out of reach of children and the dangers of iron overdose.
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Showing 15 of 15 ingredients
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Vitamin
Biotin
Vitamin B7
Water-soluble B-vitamin for hair, skin, and nail health. FDA RDI 30 mcg/day. Common in beauty and beauty-from-within supplements.
RDI 30 mcgVoluntary1 Form
Used in 1 Template3 FDA Q&A
MineralMANDATORY
Calcium
Most abundant mineral in the body; essential for bone density. FDA RDI for adults 4+ is 1,300 mg per day. MANDATORY declaration per 21 CFR 101.36(b)(2).
RDI 1,300 mgMandatory4 Forms
Used in 2 Templates4 FDA Q&A
Amino Acid
Creatine Monohydrate
N-(Aminoiminomethyl)-N-methylglycine monohydrate
Amino acid derivative for ATP regeneration in muscle. No FDA RDI; declared with † symbol. Typical dose 3-5 g per day.
RDI † not establishedVoluntary4 Forms
Used in 1 Template4 FDA Q&A
MineralMANDATORY
Iron
Essential mineral for oxygen transport. FDA RDI for adults 4+ is 18 mg per day. Mandatory declaration per 21 CFR 101.36(b)(2).
RDI 18 mgMandatory4 Forms
Used in 1 Template4 FDA Q&A
Amino Acid
L-Theanine
γ-Glutamylethylamide
Amino acid from green tea; promotes calm focus without sedation. No FDA RDI; declared with † symbol. Typical dose 100-200 mg per day.
RDI † not establishedVoluntary2 Forms
Used in 2 Templates3 FDA Q&A
Botanical
Lion's Mane
Hericium erinaceus
Medicinal mushroom used for cognitive support. No FDA RDI; declared with † symbol. Common extracts: 10:1, 8:1 dual extract.
RDI † not establishedVoluntary4 Forms
Used in 1 Template3 FDA Q&A
Mineral
Magnesium
Essential mineral involved in 300+ enzymatic reactions. FDA RDI for adults 4+ is 420 mg per day. Common forms include glycinate, citrate, and oxide.
RDI 420 mgVoluntary4 Forms
Used in 2 Templates4 FDA Q&A
Other Ingredient
Melatonin
Hormone regulating sleep-wake cycles. No FDA-established RDI; declared as "† Daily Value not established" on Supplement Facts labels.
RDI † not establishedVoluntary3 Forms
Used in 1 Template4 FDA Q&A
Botanical
Turmeric (Curcumin)
Curcuma longa
Botanical extract with anti-inflammatory properties. No FDA RDI; declared with † symbol. Standardized to 95% curcuminoids.
RDI † not establishedVoluntary4 Forms
Used in 1 Template3 FDA Q&A
Vitamin
Vitamin B12
Cyanocobalamin / Methylcobalamin
Water-soluble vitamin essential for nerve function and red blood cell formation. FDA RDI for adults 4+ is 2.4 mcg per day.
RDI 2.4 mcgVoluntary3 Forms
Used in 1 Template3 FDA Q&A
Vitamin
Vitamin C
Ascorbic Acid
Water-soluble antioxidant vitamin. FDA RDI for adults 4+ is 90 mg per day. Common forms: ascorbic acid, sodium ascorbate, calcium ascorbate.
RDI 90 mgVoluntary4 Forms
Used in 2 Templates3 FDA Q&A
VitaminMANDATORY
Vitamin D3
Cholecalciferol
Fat-soluble vitamin essential for calcium absorption and bone health. FDA RDI for adults 4+ is 20 mcg (800 IU) per day.
RDI 20 mcgMandatory2 Forms
Used in 1 Template4 FDA Q&A
Vitamin
Vitamin K2
Menaquinone
Fat-soluble vitamin that directs calcium to bones. FDA RDI 120 mcg/day. Often paired with Vitamin D3 for bone and cardiovascular health.
RDI 120 mcgVoluntary2 Forms
Used in 1 Template3 FDA Q&A
Mineral
Zinc
Trace mineral essential for immune function and wound healing. FDA RDI for adults 4+ is 11 mg per day. Common forms: picolinate, citrate, gluconate.
RDI 11 mgVoluntary4 Forms
Used in 1 Template3 FDA Q&A
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