Amazon Supplement Facts Labels That Don't Get Rejected

Amazon requires the Supplement Facts panel in listing images to be legible at thumbnail size. Photos of labels taken at an angle, low-resolution scans, or panels with tiny fonts are routinely rejected during category approval. Amazon reviewers must be able to read every ingredient and %DV value.

ReguSift fix: ReguSift exports vector SVG (scales infinitely without blur) and 2x/3x PNG (2400px+ width). Crisp at any thumbnail size Amazon renders.

Ref: Amazon Supplemental Facts image policy; FDA 21 CFR 101.36 (legibility)

Amazon reviewers cross-check %DV values against FDA RDI tables. Labels with mathematically incorrect %DV (e.g., Vitamin D3 25 mcg shown as 50% instead of 125%), or missing %DV for nutrients that have an established RDI, trigger rejection. Rounding errors per 21 CFR 101.36(b)(2)(iii) are also flagged.

ReguSift fix: ReguSift auto-calculates %DV from FDA RDI values and applies correct rounding rules per (b)(2)(iii). The built-in FDA rounding calculator validates every value before export.

Ref: FDA 21 CFR 101.36(b)(2)(iii); FDA RDI table (21 CFR 101.9(c)(8)(iv))

FDA requires that when a supplement contains certain nutrients, the panel must declare Vitamin D, calcium, iron, and potassium if present above threshold. Amazon reviewers trained on FDA rules reject panels that omit these mandatory declarations even when the rest of the label is compliant.

ReguSift fix: ReguSift automatically flags missing mandatory nutrients and prompts you to declare them. The compliance checker scans your label against the full 21 CFR 101.36 mandatory list before export.

Ref: FDA 21 CFR 101.36(b)(2)(i); Amazon supplement category review checklist

FDA 21 CFR 101.36(b)(3) requires proprietary blend constituents listed in descending order by weight (mg). Amazon reviewers reject blends where constituents appear in arbitrary or alphabetical order, or where individual constituent amounts are shown (which is prohibited).

ReguSift fix: The Proprietary Blend Formatter auto-sorts constituents by weight in descending order and removes individual amounts, producing FDA-compliant output in seconds.

Ref: FDA 21 CFR 101.36(b)(3)(ii)

Amazon may request your Certificate of Analysis during category approval. If the ingredient amounts on the Supplement Facts panel do not match the COA values, the listing is rejected. Common causes: transcription errors, unit confusion (mg vs mcg), or serving-size mismatches between COA and label.

ReguSift fix: ReguSift extracts ingredient data directly from your COA via AI + OCR, eliminating manual transcription. The original COA values are preserved as audit-trail evidence alongside the generated label.

Ref: Amazon supplement category approval documentation requirements

Amazon prohibits disease claims ("treats diabetes", "cures anxiety"), drug claims, and certain structure-function claims in supplement listings. Even if the Supplement Facts panel itself is compliant, risky claims in the title, bullets, or description cause listing rejection or takedown.

ReguSift fix: ReguSift’s optional claim scanner reviews your listing copy (title, bullets, description) against FDA, FTC, and Amazon policy rules, flagging risky language before you publish.

Ref: Amazon Supplements Policy; FTC advertising substantiation; FDA 21 CFR 101.93(g)

Serving size must use FDA-compliant units (e.g., "2 Capsules", "1 Scoop (10 g)") and servings per container must be declared. Amazon rejects labels with missing servings-per-container, inconsistent serving units, or cut-off values from a poorly cropped image.

ReguSift fix: ReguSift enforces serving size and servings-per-container as required metadata, with format validation. Exported images include the complete panel with no cut-off values.

Ref: FDA 21 CFR 101.36(b)(1); Amazon listing image completeness requirements